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Ophthalmology and Visual Sciences

Primary acquired melanosis (PAM)

Primary acquired melanosis (PAM)

Category(ies): Cornea
Contributor: Jesse Vislisel, MD
Photographer: Brice Critser

Primary acquired melanosis (PAM) is an acquired pigmentation of the conjunctival epithelium. It is analagous to lentigo maligna of the skin and carries a risk of malignant transformation. PAM appears as unilateral, patchy areas of flat, brown pigmentation within the superficial conjunctiva. The areas may wax and wane over time.