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Ophthalmology and Visual Sciences

Giant cell arteritis

Giant cell arteritis

Category(ies): Pathology
Contributor: Meagan Seay, DO and Nasreen Syed, MD

Granulomatous inflammation can occur in the blood vessel wall leading to occlusion. Temporal artery biopsy is performed for diagnosis. A long specimen (at least 2 cm) is important due to skip lesions.

Giant Cell arteristis Verhoeff-Van Gieson stain shows disruption of the internal elastic lamina.
Verhoeff-Van Gieson stain shows disruption of the internal elastic lamina.