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Ophthalmology and Visual Sciences

Band Keratopathy

Band Keratopathy

Category(ies): Cornea
Contributor: Jesse Vislisel, MD
Brice, Critser, CRA

Calcific band keratopathy (BK) results from calcium hydroxyapetite deposition in the superficial cornea, mainly Bowman layer. It can be caused by chronic ocular inflammation, hypercalcemia, hyperphosphatemia, chronic exposure to mercurial vapors or preservatives, silicone oil, primary hereditary transmission. It is often idiopathic. BK usually begins as fine, yellow-white deposits in the periphery that may coalesce over time to form a horizontal band across the cornea.

Figure 1.

Calcific band keratopathy secondary to hyperparathyroidism

band keratopathy hyperparathyr
Figure 1-A
band  keratopathy hyperparathyr slit lamp
Figure 1-B
band keratopathy hyperparathy
Figure 1-C

Figure 2.

Early band keratopathy in a patient with uveitis associated with juvenile idiopathic arthritis. The accompanying iron line denotes the chronicity of these corneal changes.

band keratopathy hyperparathy
Figure 2-A
band keratopathy hyperparathy
Figure 2-B

Figure 3.

Late band keratopathy with a chalky, white consistency.


Figure 4.

Band keratopathy in a patient with HLA-B27-associated anterior uveitis. The "Swiss cheese" appearance derives from lucent "holes" in the calcific pattern due to corneal nerve penetration through Bowman's layer.

band keratopathy hyperparathy
Figure 4-A
band keratopathy hyperparathy
Figure 4-B

Figure 5.

Calcific band keratopathy

band keratopathy hyperparathy
Figure 4-B